In a letter to nominees, the show's producers said they had gone to "great lengths to provide a safe and enjoyable evening for all of you in person".
The ceremony will break ranks with this year's Golden Globes and Emmys where winners accepted their awards via Zoom as part of Covid-19 safety measures.
The 93rd Academy Awards are due to take place on 25 April in Los Angeles.
The letter, published by US showbiz website Deadline, laid out the vision of the awards from producers Steven Soderbergh, Stacey Sher and Jesse Collins.
"For those of you unable to attend because of scheduling or continued uneasiness about travelling, we want you to know there will not be an option to Zoom in for the show," it said.
"We are going to great lengths to provide a safe and enjoyable evening for all of you in person, as well as for all the millions of film fans around the world, and we feel the virtual thing will diminish those efforts."
They said the event would include on-site Covid-19 safety teams with testing capability.
"There will be specific instructions for those of you travelling in from outside of Los Angeles, and other instructions for those of you who are already based in Los Angeles," the letter said. "This will all come directly to you from the Academy to ensure you have a safe, carefree evening (a glimpse of the future?)"
The producers also asked nominees not to be casually dressed - another break from awards such as the Golden Globes where some winners appeared in very laid-back attire.
"We're aiming for a fusion of inspirational and aspirational, which in actual words means formal is totally cool if you want to go there, but casual is really not," the letter read.
The Academy itself - the body that oversees the Oscars - has promised an "intimate" ceremony carried out under strict Covid-19 precautions.
Proceedings will take place at both the Dolby Theatre, the ceremony's normal home, and Los Angeles' main railway hub, Union Station.
According to Deadline, the Academy will host a 90-minute preshow gathering at the Union Station courtyard for nominees and their guests.